BDBM31892 9-cis retinoic acid::9C-RA::CHEMBL705::Panretin::alitretinoin
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
InChI Key InChIKey=SHGAZHPCJJPHSC-ZVCIMWCZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 31892
Affinity DataKi: 3.80nMAssay Description:Agonistic activity of the compound towards retinoid X receptor-betaMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 7.40nMAssay Description:Inhibition of [3H]-9-cis-RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of [3H]-Targretin binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]-9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]-9-cis-RA binding to mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Binding affinity against retinoic Acid X beta receptors cotransfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Effective concentrations against Retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity against retinoic Acid X beta receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Dissociation constant for binding to Retinoid X receptor betaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Transcriptional activation of Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: 15nMAssay Description:Inhibition of [3H]-9-cis RA binding to Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Inhibition of [3H]-9-cis-retinoic acid binding to baculovirus expressed retinoic acid receptor RXR-betaMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity for retinoic acid receptor RXR beta in transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoid X receptor gamma using transactivation a...More data for this Ligand-Target Pair
Affinity DataEC50: 128nMAssay Description:Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity at human RXR-beta expressed in U2OS cells by PathHunter assayMore data for this Ligand-Target Pair